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Tag: Cancer: Leukemia

Fewer Complications Seen With Vitamin C, D Supplementation in AML

Overall survival did not differ, but significant interaction found between supplementation and NPM1 with survival

Risks for MDS/Leukemia Increased for Survivors of Common Lymphoid Neoplasms

Risks for therapy-related myelodysplastic syndrome/acute myeloid leukemia elevated, but risks lower in recent years

Misdiagnosis Common for Suspected Myelodysplastic Neoplasms

About one-third of cases were reclassified following central review; receipt of inappropriate meds reported in 7 percent of misdiagnosed cases

Leukemia With IKZF₁ Deletion Benefits From Prolonged Maintenance Therapy

Prolonged maintenance therapy for IKZF₁del improved five-year cumulative risk for relapse and event-free survival

Spleen Volume Linked to Outcome After HSCT for Leukemia Patients

Higher spleen volume tied to inferior overall survival and increased incidence of nonrelapse mortality for patients with AML undergoing hematopoietic stem cell transplant

Overweight/Obese BMI Linked to Worse Survival in Young People With Leukemia

Adolescent, young adult patients with overweight/obese BMI also have higher rates of grade III/IV hepatotoxicity, hyperglycemia

Allogeneic Hematopoietic Cell Transplant Outcomes Improved From 2005 to 2019

Findings among patients with acute myeloid leukemia and second complete remission

Fixed-Duration Ibrutinib Plus Venetoclax Beneficial for Leukemia

Overall response rates >95 percent, regardless of high-risk features; 36-month PFS 88 and 92 percent for those with, without high-risk features

Venetoclax-Obinutuzumab With, Without Ibrutinib Superior in Leukemia

Combination better than chemoimmunotherapy for percentage with undetectable minimal residual disease, PFS in chronic lymphocytic leukemia

Blinatumomab Safe, Efficacious for Infants With KMT2A-Rearranged Leukemia

No toxic effects seen meeting definition of primary end point; profile of toxic effects consistent with that reported in older patients