Advertisement
Home Tags Cancer: Colon

Tag: Cancer: Colon

The risk for colorectal cancer death drops with an increasing number of prediagnostic colonoscopies

Prediagnostic Colonoscopy Cuts Colorectal Cancer Death Risk

Mortality risk drops 17 percent with one colonoscopy before diagnosis, 45 percent with three colonoscopies
A triplet combination of therapies (encorafenib

Triplet Tx Ups Survival in BRAF V600E-Mutated Colorectal Cancer

Overall survival longer for encorafenib, cetuximab, and binimetinib combo versus standard therapy
Delay in referral for colorectal cancer in primary care is associated with low cancer suspicion

Low Cancer Suspicion Tied to Delay in CRC Referral in Primary Care

Presentation without alarm symptoms linked to long duration to referral in multivariable analysis
For patients with colorectal adenomas

High-Intensity Surveillance of Colorectal Adenomas Modeled

Model shows high-intensity surveillance could provide modest, clinically relevant benefits at acceptable cost
There is considerable variability in colorectal cancer mortality disparities across urban cities

Colorectal Cancer Mortality Disparities Vary Across U.S. Cities

Racial disparities in 25 of 30 cities examined; highest disparity in Washington, D.C., lowest in Philadelphia
Among younger adults

Incidence of Colorectal Cancer Up in Younger Adults Worldwide

In most high-income countries with long-term data, uptick in early-onset disease began in mid-1990s
For patients with advanced/metastatic colorectal cancer

Physical Activity, Overall Survival Not Linked in Metastatic CRC

Nine or more MET hours per week tied to lower risk for grade ≥3 treatment-related adverse events
Oral antibiotic use is associated with an increased risk for colon cancer and a reduced risk for rectal cancer

Oral Antibiotic Use Linked to Risk for Colorectal Cancer

Risk for colon cancer increased, risk for rectal cancer reduced in association with oral antibiotic use
Younger patients with colorectal cancer are more likely to present with abdominal pain and via an emergency

Younger CRC Patients More Likely to Present With Abdominal Pain

Young colorectal cancer patients more often present via emergency; have lowest percentage early-stage cancer
From 2004 to 2015

Proportion of CRC Diagnoses Increased in Adults Younger Than 50

Younger adults presenting with colorectal cancer present with more advanced disease than older adults