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Tag: Anticoagulants

ASA: Door-to-Treatment Time Tied to Survival in Anticoagulation-Linked ICH

Reduced mortality and discharge to hospital seen with DTT of 60 minutes or less among ICH patients receiving anticoagulation reversal

Ischemic Strokes Less Severe With Left Atrial Appendage Closure in A-Fib

Ischemic stroke less often disabling or fatal with left atrial appendage closure than direct oral anticoagulant prophylaxis

Bleeding Higher With Standard-Dose DOACs in Nonvalvular A-Fib

Higher rate of bleeding seen with standard- versus reduced-dose DOACs in patients 65 years and older

Incident A-Fib Linked to Increased Risk of Mild Cognitive Impairment

Risk of MCI not increased for patients with incident a-fib receiving digoxin treatment or anticoagulant and amiodarone treatment

DOACs Reduce Dementia Risk Versus Warfarin in A-Fib

Significant reductions were seen in dementia risk for rivaroxaban, apixaban, and dabigatran versus warfarin in network meta-analysis

Apixaban Has Lower Bleeding Risk for Initial Anticoagulation for Venous Thromboembolism

During extended treatment, bleeding risk was similar for apixaban and rivaroxaban

Prolonged Direct Oral Anticoagulants Beneficial for Preventing Recurrent VTE

Findings seen among adults prescribed warfarin, DOACs beyond six months after acute venous thromboembolism

Ticagrelor-Acetylsalicylic Acid More Beneficial for Obese With Minor Stroke, TIA

Significantly lower rate of stroke within 90 days seen for ticagrelor-ASA versus clopidogrel-ASA for those carrying CYP2C19 loss-of-function allele

Anticoagulants Do Not Reduce Arterial Thrombotic Event Risk in Cancer

No reduction seen in risk of antithrombotic events but increased risk of major and minor bleeding

Benefits of Indefinite Anticoagulant Unclear After First VTE

Indefinite anticoagulation prevented recurrent VTE events, but induced major bleeding events