In-hospital mortality down with paracentesis use; trend toward reduction in mortality for early tx
FRIDAY, Dec. 11, 2015 (HealthDay News) — For patients admitted with diagnoses of cirrhosis and ascites, paracentesis is associated with decreased in-hospital mortality but is underutilized, according to a study published online Dec. 8 in the Journal of Gastroenterology and Hepatology.
John N. Gaetano, M.D., from the University of Chicago, and colleagues identified 31,614 adults, non-electively admitted with diagnoses of cirrhosis and ascites. Utilization and outcomes of paracentesis were examined.
The researchers found that 51 percent of the hospitalized patients underwent paracentesis. The overall in-hospital mortality rate was 7.6 percent, with increased mortality seen among patients who did not versus those who did undergo paracentesis (8.9 versus 6.3 percent; P < 0.001). In-hospital mortality was 1.83-fold higher for patients who did not receive paracentesis versus those who did receive paracentesis. There was a reduction in mortality for early paracentesis versus late paracentesis (5.5 versus 7.5 percent). Less frequent use of early paracentesis was seen for patients admitted on a weekend (50 versus 62 percent for those admitted on a weekday; adjusted odds ratio, 1.12). Early paracentesis correlated with shorter length of stay and decreased hospitalization costs among patients diagnosed with spontaneous bacterial peritonitis (both P < 0.001).
“[These data support] the use of paracentesis as a key inpatient quality measure among hospitalized adults with cirrhosis,” the authors write. “Future studies are needed to investigate the barriers to paracentesis use on admission.”
Full Text (subscription or payment may be required)
Copyright © 2015 HealthDay. All rights reserved.