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In a new American Academy of Neurology guideline published in the May 7 issue of Neurology

Recommendations Issued for Treating Tourette Syndrome

Guidelines based on systematic review, focus on individualized treatment decisions
In young American Indians

Arsenic Exposure Linked to Changes in Heart Structure

Arsenic in drinking water linked to LV hypertrophy, especially for prehypertensive, hypertensive
Most patients with rheumatoid arthritis (RA) experience functional disability that may precede RA diagnosis and persist throughout the disease course

Disability Often Precedes Rheumatoid Arthritis Diagnosis

Functional disability continues even after diagnosis and treatment
Efforts are needed to ensure all completed large trials are reported

Efforts Needed to Ensure Publication of All Trials

67 trials ID'd that were unreported for median of nine years after completion, with 87,883 participants
The average price for single-source brand-name drugs is higher in the United States than in other countries

External Reference Pricing Could Cut Drug Costs in U.S.

Prices averaged 3.2 to 4.1 times higher in U.S.; differential varied from 1.3 to 70.1 for individual drugs
The Combat Application Tourniquet is suitable for use in the upper and lower extremities of school-age children

Combat Application Tourniquet Suitable for Use in Children

CAT successfully occluded arterial blood flow in all upper extremities, 93 percent of lower extremities
For patients undergoing neoadjuvant chemotherapy for locally advanced breast cancer

New Lesions ID’d on Breast MRI During Treatment Likely Benign

New suspicious lesions detected on breast MRI during neoadjuvant therapy are more likely benign
Low body mass index among men entering adult life is associated with an increased incidence of Crohn disease and ulcerative colitis up to 40 years later

In Men, Low BMI Tied to Later Inflammatory Bowel Disease

Risk lasts through 40 years of adulthood for underweight adolescent men
Plant-based diets are associated with a lower risk for heart failure in adults without known heart disease

Plant-Based Diets Tied to Lower Risk for Heart Failure

Southern dietary pattern of more fried food and sweetened beverages tied to higher risk
Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules have been approved to treat adults with cardiomyopathy caused by transthyretin mediated amyloidosis

FDA Approves Treatments for Heart Failure Caused by Rare Disease

Capsules approved to treat cardiomyopathy caused by transthyretin mediated amyloidosis