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Esketamine nasal spray plus an oral antidepressant appears to be a safe and effective treatment for patients with treatment-resistant depression

Esketamine Nasal Spray May Improve Refractory Depression Outcomes

Findings seen among outpatients with treatment-resistant depression using combo nasal spray, oral antidepressant
Low-density lipoprotein cholesterol is associated with the probability of developing early-onset Alzheimer disease

Higher LDL-C Levels Linked to Early-Onset Alzheimer Disease

Cases with EOAD have higher levels of LDL-C, greater frequency of rare genetic coding variants of APOB
Less than 60 percent of prescriptions for the treatment of sexually transmitted infections among teens seeking care in the emergency department are filled

Noncompliance Common in Teens Prescribed STI Treatment in ED

Prescriptions often go unfilled; hospital admission is the only factor associated with prescription filling
Exercise and/or behavioral treatment interventions may provide clinically meaningful improvements in depression outcomes in adults with type 2 diabetes and major depressive disorder

Exercise, Therapy May Improve Depression, Diabetes Outcomes

Exercise and cognitive behavioral therapy can improve depression outcomes in adults with type 2 diabetes
Clinical guidelines on adjuvant and salvage radiotherapy after radical prostatectomy have been updated

Guidelines Updated for Radiotherapy After Prostatectomy

Updates include adjuvant radiotherapy for patients with adverse pathologic findings, hormonal therapies
The first test to detect the Zika virus in human blood has been approved by the U.S. Food and Drug Administration.

FDA Approves First Test for Zika in Human Blood

The ZIKV Detect 2.0 IgM Capture ELISA is made by Seattle-based InBios
About half of immunosuppressed persons reported participating in cleanup activities following Hurricane Harvey

Many Immunosuppressed Persons Join in Hurricane Cleanup

Use of respirators low, with about half of those engaged in heavy cleanup wearing respirator
A tool has been developed that can improve standardization and transparency when describing cell therapies

Experts Develop Standardized Tool for Describing Cell Therapies

Consensus reached on contents of DOSES tool for improving standardization and transparency
Generally

Mammogram Benefits Seen as More Important Than Harms

Perception varies by knowledge of latest recommendations, date of last mammogram
There is a looming critical shortage of pediatric nurse practitioners

Pediatric Nurse Practitioner Shortage Looming

White paper calls for research on practice and policy to support maximizing contributions of PNPs