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The addition of budesonide to a saline nasal lavage for the treatment of chronic rhinosinusitis provides clinically meaningful benefits

Budesonide With Saline Solution Helpful for Rhinosinusitis

Clinically meaningful benefits seen in chronic rhinosinusitis patients; treatment effect imprecise
High rates of Salmonella contamination have been identified in kratom products collected and tested since February 2018

High Rates of Salmonella Contamination ID’d in Kratom

As of end of May 2018, 199 cases of salmonellosis ID'd that were linked to kratom consumption
Intravenous acetaminophen does not decrease opioid utilization to a clinically significant threshold among colectomy patients

IV Acetaminophen Minimally Helpful for Colectomy Pain

IV acetaminophen has similar effectiveness to oral doses and doesn't meaningfully cut opioid use
Cabozantinib results in significantly longer overall and progression-free survival than placebo among patients with advanced hepatocellular carcinoma

Cabozantinib Improves Survival in Advanced Hepatocellular Cancer

Significantly longer overall and progression-free survival with cabozantinib than placebo
Yale Medicine is effectively targeting electronic health record use and functionality as a way to improve physician job satisfaction and reduce burnout

IT Solutions for Easier EHRs Save Physicians Time, Burnout

These solutions improve EHR user interface with easier login identification, voice recognition
Cumulative reductions in federal payments to hospitals from 2010 to 2028 are estimated to reach $218.2 billion

Hospitals Face $218B in Federal Payment Cuts From 2010 to 2028

11 pieces of legislation plus regulatory changes result in payment reductions beyond those under ACA
For patients with hereditary transthyretin amyloidosis with polyneuropathy

Patisiran, Inotersen Aid Hereditary Transthyretin Amyloidosis

Improvement in modified Neuropathy Impairment Score+7, Norfolk QoL Diabetic Nephropathy score
In 2013

1996 to 2013 Saw Large Increase in Diabetes Spending

Increased spending per encounter has been the biggest driver of overall rise in spending
Anticonvulsant drugs are ineffective for chronic low back pain and can cause harm

Anticonvulsants Seem to Be Ineffective for Low Back Pain

And, gabapentinoids have a higher risk for adverse events
For women after vaginal birth

For Postpartum Hemorrhage, Carbetocin Similar to Oxytocin

Heat-stable carbetocin non-inferior for preventing blood loss of ≥500 ml, use of other uterotonic agents