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The expiration dates of certain batches of EpiPens have been extended by the U.S. Food and Drug Administration in an effort to reduce shortages of the life-saving devices.

FDA Extends EpiPen Expiration Dates to Tackle Shortage

Shortages due to factors such as supply disruptions and manufacturer issues
Many low-income urban preschool-aged children with asthma do not meet the criteria for home medication readiness

Many Children With Asthma Do Not Have Medications Ready

Low-income urban preschoolers with asthma may not meet home medication readiness criteria
Life expectancy has declined in recent years in some high-income countries

Declines in Life Expectancy in Many High-Income Countries

And increase in midlife death rates across racial and ethnic groups in the United States
Knowing payer policies and regulatory requirements is critical to appealing denials

Experts Offer Tips for Provider Appeal of Denied Medical Claims

Recommendations include asking for exceptions to payer policies and citing regulatory information
Concomitant exposure to pregabalin and opioids is associated with increased odds of opioid-related death

Odds of Death Up With Exposure to Pregabalin, Opioids

Dose-response association with highest odds of opioid-related death with high-dose pregabalin
From 2014 to 2017 there was an increase in tianeptine exposure calls reported by poison control centers to the National Poison Data System

CDC: Increase in Tianeptine Exposures From 2014 to 2017

Most commonly reported health effects were neurologic, cardiovascular, and gastrointestinal
Significant improvements in neonatal abstinence syndrome outcomes can result from a comprehensive quality improvement program

QI Program Can Up Outcomes for Neonatal Abstinence Syndrome

Decreases in pharmacologic treatment, adjunctive agent use, hospital length of stay, opioid tx days
Ingesting honey after swallowing a button battery may reduce injuries and improve outcomes in children

Honey May Protect Children Who Swallow Button Batteries

Honey and Carafate appear to rapidly protect against batteries' caustic effects
The first generic version of the EpiPen has been approved by the U.S. Food and Drug Administration

FDA Approves First Generic EpiPen

Approval will address both rising costs and shortages of epinephrine
A U.S. National Institutes of Health oversight panel will no longer review all applications for gene therapy experiments. Instead

Comments Open on End of NIH Review for Gene Therapy Studies

NIH oversight panel no longer plans to review all applications for gene therapy experiments