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Transplanting hepatitis C virus-infected kidneys into uninfected recipients and then treating patients with antiviral therapy leads to a higher quality of life and is less costly than waiting for transplantation with an uninfected kidney

Model Shows Hep C-Infected Kidney Transplants Beneficial, Cost-Effective

Transplant plus antiviral therapy improves quality of life, reduces health care costs for recipients
Older age is associated with an increased risk for bacteremia in hospitalized patients with inflammatory bowel disease

Bacteremia Risk Higher in Older Patients Hospitalized With IBD

No association seen between bacteremia and inflammatory bowel disease-related medications
Legally dispensed marijuana products have stronger concentrations of tetrahydrocannabinol and cannabidiol than needed for chronic pain relief

Many Legal Marijuana Products Too Strong for Treating Pain

Majority of products in medicinal, recreational programs advertised to have >15 percent THC
Deep early remission of Crohn disease is associated with a significant decrease in long-term adverse effects

Early Deep Remission of Crohn Disease Tied to Better Outcomes

Findings show significant decrease in adverse outcomes over three years of follow-up
Following nonmajor orthopedic surgery of the lower limb

Rivaroxaban Prevents VTE After Lower-Limb Surgery

Rivaroxaban superior to enoxaparin for preventing major VTE after nonmajor orthopedic surgery

American College of Cardiology, March 28-30

The American College of Cardiology 69th Annual Scientific Session and Expo The annual meeting of the American College of Cardiology was held virtually...
A number of institutions this week announced their participation in an international clinical drug trial evaluating the safety and efficacy of remdesivir in hospitalized patients with the novel coronavirus 2019.

Enrollment Begins in NIH-Sponsored Trial of Remdesivir for COVID-19 Patients

Institutions also announce enrollment in study evaluating efficacy of sarilumab for hospitalized COVID-19 patients
Microneedle array delivery of trimeric coronavirus spike protein subunit vaccines seems promising for immunization against severe acute respiratory syndrome coronavirus 2 infection

Test Vaccine Elicits Strong Ab Response to SARS-CoV-2 in Mice

Microneedle array-delivered S1 subunit vaccine elicits potent antigen-specific antibody response in mice
Here are what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 30 to April 3

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
Proton pump inhibitors taken for acid reflux may lead to an increased risk for fractures in children and adolescents

Proton Pump Inhibitor Therapy May Up Fracture Risk in Children

Fracture risk remained higher after adjusting for differences in sex, race, other factors