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Immunotherapy with CD19 chimeric antigen receptor-modified T cells in a defined CD4+/CD8+ ratio can lead to improved disease response and overall and progression-free survival

Remission Up With T Cell Therapy for Non-Hodgkin’s Lymphoma

Researchers identify treatment characteristics that correlate with therapeutic response, toxicity
Fibroblast growth factor 21 genotypes may interact with dietary macronutrient intake to affect central adiposity and body fat composition

FGF21, Dietary Intake Interaction Impacts Adiposity

FGF21 genotype interacts with dietary carbohydrate/fat intake to affect adiposity, body fat
Taking antibiotics at a very young age could increase the risk of certain allergic conditions later in life

Early Exposure to Antibiotics Ups Risk of Allergic Dz Later in Life

Researchers found higher risk for hay fever, eczema in those exposed to antibiotics before age 2
Higher levels of free thyroxine may indicate a greater risk of sudden cardiac death

Free Thyroxine Hormone Levels Linked to Sudden Cardiac Death

Even patients with levels at the high end of the normal range more likely to experience SCD
For patients with asthma

Review Finds Vitamin D Beneficial for Patients With Asthma

Reduction in rate of exacerbations requiring systemic corticosteroids or requiring ER/hospital visit
Atrial fibrillation is associated with a wider range of conditions than previously believed

A-Fib Contributes to Wide Range of Other Health Conditions

Review links atrial fibrillation to increased risk for cardiovascular events, kidney disease, not just stroke
Ovarian cancer mortality is down dramatically in many parts of the world

Oral Contraceptives May Be Cause of Drop in Ovarian CA Mortality

Rates down 16 percent in U.S., 8 percent in Canada, and 10 percent in Europe over a decade
Patients with type 1 diabetes have more diabetes-associated autoantibodies (DAAs) and non-DAAs than patients with type 2 diabetes

More Diabetes-Associated, Non-Associated Autoantibodies in T1D

Systemic immune mediators negatively correlated with diabetes-associated autoantibody titers
The American Academy of Family Physicians has graded the recommendation for colorectal cancer screening as a B recommendation

AAFP Downgrades USPSTF CRC Screening Recommendation

AAFP recommends fecal immunochemical tests, flexible sigmoidoscopy, colonoscopy
Increasing trends of endogenous Klebsiella pneumoniae endophthalmitis have been reported in Australia

Rise in Endogenous Klebsiella pneumoniae Endophthalmitis

Rising trends of EKPE in major centers in Australia; source of sepsis was hepatic abscess in all cases