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Sleep-disordered breathing is associated with increased likelihood of cognitive impairment

Review Links Sleep-Disordered Breathing, Cognitive Impairment

SDB also associated with worse executive function in pooled analysis of seven cross-sectional studies
The majority of melanomas arise from new lesions rather than existing moles

Most Melanomas Don’t Start As Existing Moles

More than two-thirds occur as new lesions, researchers find
The U.S. Food and Drug Administration on Wednesday approved the first gene therapy -- Kymriah (tisagenlecleucel) -- in the United States

FDA Approves First Gene Therapy in the United States

Kymriah approved for patients up to 25 years of age with refractory or relapsed B-cell precursor ALL
Clinical benefit of reduced low-density lipoprotein cholesterol levels may depend on the corresponding reduction in apolipoprotein B-containing lipoprotein particles

ApoB Levels More Closely Tied to Reduced CVD Events Than LDL

Change in apoB levels may be better predictor of clinical response than LDL-C, HDL-C levels
Severe vaccine reactions recur rarely

Low Rate of Recurrence Seen for Serious Reactions to Vaccines

Findings add to evidence of safety of childhood immunizations, pediatricians say
Women with a genetic predisposition for Alzheimer's disease face a 10-year window -- between ages 65 and 75 -- when they have far greater chances of developing the disease than men with similar genetic risks

Gender-Specific High-Risk ‘Window’ Seen in Alzheimer’s

Women genetically predisposed to Alzheimer's more susceptible than men from 65 to 75 years of age
A Florida stem cell clinic has received a warning letter from the U.S. Food and Drug Administration about what the agency describes as serious problems that could pose health risks to patients.

FDA Cites ‘Significant Deviations’ at Florida Stem Cell Clinic

Agency concerned about 'significant deviations from current good manufacturing practice requirements'
A novel genetic variant has been identified in the IGF2 gene among a Latino population that is associated with reduced risk for type 2 diabetes

Novel Genetic Variant in IGF2 Linked to Reduced T2DM Risk

Variant is associated with allele-dosage dependent reduction in IGF2 isoform 2 expression
End-tidal carbon dioxide levels are prognostic for patients with chronic thromboembolic pulmonary hypertension

Tidal CO2 Prognostic for Chronic Thromboembolic Pulmonary HTN

ETCO2 dichotomized at 29 mm Hg significantly associated with reduced overall survival
Higher exposure to organophosphate flame retardants is associated with reduced success of in vitro fertilization

Flame Retardants Associated With Reduced IVF Success

Link found between exposure to a certain chemical and failed in vitro fertilization attempts