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Close to half of breast cancer patients who choose to have a double mastectomy after genetic testing may not have the gene mutations known to raise the risk of additional cancers

Misunderstanding of BRCA Test Results Affects Mastectomy Rates

Half of average-risk patients with variants of uncertain significance may undergo bilateral mastectomy
The incidence of diabetes is increasing among young persons

Diabetes Continues to Be a Significant Public Health Burden

But progress seen in cardiovascular complications, mortality among these patients
There is a low risk of development of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett's esophagus of <1 cm (irregular Z line) within five years of index endoscopy

Barrett’s With Irregular Z Line Unlikely to Progress Quickly

Within five years, incident cancer cases observed only in patients with Barrett's esophagus ≥1 cm
More than one-third of Medicare beneficiaries who died in 2011 had at least four care transitions during their last six months of life

Care Transitions Common at End of Life for Medicare Recipients

More than 80 percent have at least one transition, with many experiencing four or more
Use of inhaled "poppers" -- volatile alkyl nitrite compounds inhaled for their psychoactive effects such as transient euphoria and sexual arousal -- might pose a danger to the user's vision

Recreational Drug ‘Poppers’ Linked to Retinal Damage

Legal, nitrate-based inhalant appears to harm retinal cells, causing some vision loss, researchers say
Fewer than one in three men screened with the prostate-specific antigen test for prostate cancer talked about the risks and benefits of the test with their doctor

PSA Test Often Occurs Without Discussion of Benefits, Harms

Men with lower incomes, education, and no insurance less likely to receive pretest counseling
Individuals with risk factors for cardiovascular disease and stroke in middle age are more likely to have elevated levels of amyloid

Midlife Vascular Risk Factors Associated With Elevated Amyloid

One cardiovascular risk factor alone may up the likelihood of amyloid deposits by 88 percent
Women with overactive bladder syndrome treated with antimuscarinics have increased subsequent risk of depressive disorder

Depressive Disorders Up With Antimuscarinics for OAB

Increased risk for women with overactive bladder syndrome receiving antimuscarinics
The presence of psoriatic arthritis

Specific Factors Influence First-Line Biologic Rx for Psoriasis

Presence of psoriatic arthritis, weight, employment status, baseline disease severity all affect selection
Physicians spend roughly as many hours on computer work as they do meeting with patients

Physicians Are Spending Half Their Time on Computer Tasks

Researchers estimate physicians devote 3.08 hours a day to face-to-face office visits