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Hematology and Oncology

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Close to half of breast cancer patients who choose to have a double mastectomy after genetic testing may not have the gene mutations known to raise the risk of additional cancers

Misunderstanding of BRCA Test Results Affects Mastectomy Rates

Half of average-risk patients with variants of uncertain significance may undergo bilateral mastectomy
Cancer rates differ between African- and U.S.-born black Americans

Cancer Occurrence Differs Among African-Born, U.S.-Born Blacks

Research suggests differences in environmental, cultural, social, genetic factors
There is a low risk of development of high-grade dysplasia or esophageal adenocarcinoma among patients with Barrett's esophagus of <1 cm (irregular Z line) within five years of index endoscopy

Barrett’s With Irregular Z Line Unlikely to Progress Quickly

Within five years, incident cancer cases observed only in patients with Barrett's esophagus ≥1 cm
Fewer than one in three men screened with the prostate-specific antigen test for prostate cancer talked about the risks and benefits of the test with their doctor

PSA Test Often Occurs Without Discussion of Benefits, Harms

Men with lower incomes, education, and no insurance less likely to receive pretest counseling
Metformin use in combination with docetaxel chemotherapy does not significantly improve survival in patients with diabetes and metastatic castration-resistant prostate cancer

Metformin Use Does Not Increase Prostate Cancer Survival

Drug given in combination with docetaxel chemotherapy in patients with metastatic disease
Enhanced patient-centered communication positively impacts patients' psychological state during bad-news encounters

Doctor Communication Style Key During Bad-News Encounters

Enhanced patient-centered communication lessens anxiety during disclosure of cancer diagnosis
The U.S. Preventive Services Task Force is recommending that men aged 55 to 69 have a discussion with their doctor about the pros and cons of prostate-specific antigen screening for detecting prostate cancer.

Patient Choice Stressed in Latest USPSTF PSA Screening Recs

Men aged 55 to 69 should discuss PSA screening with their doctor, panel recommends
For women with epithelial ovarian cancer

Survival Similar With Debulking by Laparotomy, Laparoscopy

Similar three-year survival rates for women with epithelial ovarian cancer undergoing debulking
Mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients

Mindfulness Practice Reduces Cortisol Blunting During Chemo

Findings in colorectal cancer patients using mindfulness practice at start of chemo sessions
Implementation of the 2006 Massachusetts health reform

Thyroidectomy for Thyroid CA Up Post 2006 Mass. Health Reform

Health reform linked to significantly increased rates of thyroidectomy and neck dissection