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Bacterial Cause of Periodontal Disease May Drive RA

Aggregatibacter actinomycetemcomitans implicated in periodontal disease and rheumatoid arthritis

THURSDAY, Dec. 15, 2016 (HealthDay News) — Specific bacteria may help explain the connection between periodontal disease and rheumatoid arthritis, according to a study published online Dec. 14 in Science Translational Medicine.

Felipe Andrade, M.D., Ph.D., an associate professor of medicine at the Johns Hopkins University School of Medicine in Baltimore, and colleagues examined 196 samples from the gums of patients with rheumatoid arthritis. The researchers looked for evidence of Aggregatibacter actinomycetemcomitans, bacteria linked to periodontal disease.

Signs of infection were detected in almost half of the rheumatoid arthritis patients compared to just 11 percent of another group of individuals without periodontal disease or rheumatoid arthritis. This finding raises the possibility that the bacteria could cause both periodontal disease and rheumatoid arthritis, the study authors suggested.

Andrade told HealthDay that “the findings strongly suggest that antibiotics can be an option for treatment of rheumatoid arthritis.”

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