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Targeting can enhance accumulation of nanoparticles to graft endothelial cells of human kidneys undergoing ex vivo normothermic machine perfusion

Targeting Ups Nanoparticle Delivery to Graft Endothelial Cells

Anti-CD31 antibody selectively enhances targeting of NPs to graft ECs of human kidney undergoing NMP
Sublocade

FDA Approves Once-Monthly Injection for Opioid Addiction

Sublocade has been shown to reduce opioid withdrawal symptoms and the desire to use opioids
Adolescents with depression who are poor responders to treatment do not have more densely connected networks

Network Density Not Linked to Response in Teen Depression

No significant association between higher network strength and poorer outcomes
From 1997 to 2014

Differences in Cancer Survival by Type of Insurance

Survival up in patients with private insurance, Medicare; no change or drop with other, no insurance
Older ophthalmologists are less likely than younger ones to receive unsolicited patient complaints

Older Ophthalmologists Less Likely to Have Patient Complaints

Risk for incurring unsolicited patient complaints higher for those aged 41 to 50, 31 to 40 versus ≥71
For stage I non-small-cell lung cancer

Lobectomy Beats SBRT Survival in Early-Stage NSCLC

Higher cancer mortality for SBRT versus lobectomy; no difference for SBRT, sublobar resection
For individuals with type 2 diabetes

Fat Intake Influences HbA1c-Lowering Effect in DPP4i Therapy

Saturated fat intake is significantly correlated with change in HbA1c during DPP4i monotherapy
An estimated 42.0 percent of all incident cancers and 45.1 percent of cancer deaths in the United States are attributed to potentially modifiable risk factors

>40% of Cancers, Cancer Deaths Due to Modifiable Risk Factors

Cigarette smoking accounts for highest proportion of cancer cases (19.0 percent), deaths (28.8 percent)
Females with anorexia nervosa have lower gut microbial diversity

Lower Microbial Diversity in the Gut in Anorexia Nervosa

Alpha diversity lower in anorexia nervosa, obese participants versus other groups; highest for athletes
The chemical stability of warfarin sodium tablets is not affected by repackaging into dose administration aids

Storage in Dose Administration Aids Doesn’t Affect Warfarin

Repackaging of warfarin sodium tablets into dose administration aids doesn't affect chemical stability