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Assessing change in the CHA2DS2-VASc score over time is more predictive of ischemic stroke in patients with atrial fibrillation than the baseline score

Follow-Up Delta CHA2DS2-VASc Score Better Predicts CVA in A-Fib

CHA2DS2-VASc score not static; most a-fib patients develop new risk factor before ischemic stroke
Higher-intensity end-of-life care may be driven by financial incentives present in fee-for-service Medicare but not in the Veteran Affairs integrated system

Intense End-of-Life Care Found to Be Less Likely for VA Patients

Authors say results have important implications for the future of VA care, Medicare policy
Children with a physical condition frequently have a mental disorder

Mental Disorders Common in Kids With Chronic Physical Conditions

Baseline multimorbidity tied to decreases in physical, psychological, and school environment quality of life
A long-term physical activity program is not associated with reduced risk of frailty among community-dwelling older adults with functional limitations

Physical Activity Doesn’t Seem to Reduce Risk of Frailty in Elderly

Baseline frailty didn't modify effect of physical activity on reducing major mobility disability
A home-based binocular falling-blocks video game does not improve visual outcomes more than placebo for children and adults with unilateral amblyopia

Binocular Video Game Doesn’t Up Visual Function in Amblyopia

No significant improvement in mean amblyopic eye visual acuity compared with placebo video game
For young adults without known risk factors

HIV Screening Most Optimal at 25 Years of Age If No Risk Factors

Simulation favors screening at 25 for adolescents, young adults without identifiable HIV risk factors
Two years of high-intensity exercise training is associated with improved maximal oxygen uptake and reduced cardiac stiffness in previously sedentary healthy middle-aged adults

CV Exercise Betters Cardiac Aging in Sedentary Middle-Aged Adults

Two years of high-intensity exercise tied to improved maximal oxygen uptake, reduced cardiac stiffness
There is an increased risk of developing cardiovascular disease among patients with idiopathic thrombocytopenic purpura

Idiopathic Thrombocytopenic Purpura Tied to Higher CVD Risk

Risk further increased among patients with ITP who undergo splenectomy
Use of an abdominal obstetric binder is associated with a faster and more effective colonoscope insertion during outpatient colonoscopy

Abdominal Obstetric Binder Helpful for Cecal Intubation

Colonoscope cecal intubation time faster and more effective; less patient-reported abdominal distension
In children who receive a non-kidney solid organ transplant

Kidney Injury Common After Non-Kidney Transplants in Children

High risk of AKI in first year after non-kidney solid organ transplant; in turn, increases CKD risk