Home Pharmacy August 2020 Briefing – Pharmacy

August 2020 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for August 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

FDA Could Green-Light COVID-19 Vaccines Before Clinical Trials Completed

MONDAY, Aug. 31, 2020 (HealthDay News) — Emergency use authorization (EUA) or approval for a COVID-19 vaccine before phase 3 clinical trials are complete could be considered by the U.S. Food and Drug Administration, according to the agency’s commissioner, Stephen Hahn, M.D.

CNN Article

Follow-up Calls After Mohs Surgery Do Not Boost Satisfaction

MONDAY, Aug. 31, 2020 (HealthDay News) — Postoperative follow-up telephone calls (TFU) to patients after Mohs micrographic surgery (MMS) do not improve patient satisfaction, according to a research letter published online July 31 in the Journal of the American Academy of Dermatology.

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Long-Term Follow-Up Reported for BP Telemonitoring Program

MONDAY, Aug. 31, 2020 (HealthDay News) — Among adults with uncontrolled blood pressure, fewer cardiovascular events and lower costs were observed at five years with a pharmacist-led telemonitoring program, but the differences were not statistically significant compared with usual care, according to a study published online Aug. 31 in Hypertension.

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Use of Performance-Enhancing Substances Tied to Risk Behaviors

MONDAY, Aug. 31, 2020 (HealthDay News) — Use of legal performance-enhancing substances (PES) in young adults is associated with an increased likelihood of future problematic alcohol use and drinking-related risk behaviors, according to a study published online Aug. 31 in Pediatrics.

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Vitamin C Positively Linked to Skeletal Muscle Mass Measures

FRIDAY, Aug. 28, 2020 (HealthDay News) — Dietary and circulating vitamin C are positively associated with measures of skeletal muscle mass in middle- and older-aged men and women, according to a study published online Aug. 27 in The Journal of Nutrition.

Abstract/Full Text

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 24 to 28, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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FDA Warns of Hand Sanitizers in Food-Like Packaging

FRIDAY, Aug. 28, 2020 (HealthDay News) — A warning about alcohol-based hand sanitizers in packaging that looks like food or drink has been issued by the U.S. Food and Drug Administration.

More Information

Model Says COVID-19 Deaths Could Surpass 317,000 by December

FRIDAY, Aug. 28, 2020 (HealthDay News) — A widely cited model for COVID-19 deaths in the United States predicts a total of 317,000 deaths by December.

CNN Article

Early Use of Empiric Antibacterial Therapy Common in COVID-19

FRIDAY, Aug. 28, 2020 (HealthDay News) — Early empiric antibacterial therapy use is high in patients hospitalized with COVID-19, according to a study published online Aug. 21 in Clinical Infectious Diseases.

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Mortality, Intubation Rates Lower With Anticoagulation in COVID-19

FRIDAY, Aug. 28, 2020 (HealthDay News) — Among hospitalized patients with COVID-19, anticoagulation (AC) is associated with reduced mortality and intubation, according to a study published online Aug. 26 in the Journal of the American College of Cardiology.

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Parents Have Contradictory Views on Childhood Vaccines

THURSDAY, Aug. 27, 2020 (HealthDay News) — The vast majority of parents believe vaccines are the best way to protect their children from infectious diseases, yet two-thirds are still nervous to take their children to their pediatrician’s office during the COVID-19 pandemic, according to the results of a survey released by Orlando Health.

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Program Improves Use of Chronic Opioid Therapy in HIV Care

THURSDAY, Aug. 27, 2020 (HealthDay News) — The TEACH (Targeting Effective Analgesia in Clinics for HIV) intervention is a promising strategy for improving adherence to opioid prescribing guidelines among HIV care providers and their patients on chronic opioid therapy (COT), according to a study published online July 22 in Clinical Infectious Diseases.

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Recovery Protocol Cuts Opioid Use After Elective Neurosurgery

THURSDAY, Aug. 27, 2020 (HealthDay News) — Enhanced recovery after surgery (ERAS) protocols can reduce postoperative use of opioids in patients undergoing elective spine and peripheral nerve surgical procedures, according to a study published online Aug. 6 in Pain Medicine.

Abstract/Full Text

Topical Calcineurin Inhibitors Not Tied to Skin Cancer

THURSDAY, Aug. 27, 2020 (HealthDay News) — There is no association between use of topical calcineurin inhibitors (TCIs) for the treatment of atopic dermatitis (AD) and an increased risk for skin cancer, according to a study published online Aug. 12 in JAMA Dermatology.

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About Half of Waivered Clinicians Prescribe Buprenorphine for OUD

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — About half of waivered clinicians prescribe buprenorphine for opioid use disorder and most treat at levels below their patient limits, according to a research letter published online Aug. 24 in JAMA Network Open.

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About One in Three Multiple Sclerosis Patients Have Migraine

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — Internationally, more than three in 10 patients with multiple sclerosis (MS) have migraine, according to a review published in the September issue of the Journal of Clinical Neuroscience.

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Escitalopram Reduces Symptoms of Anxiety in Teens With GAD

WEDNESDAY, Aug. 26, 2020 (HealthDay News) — For adolescents with generalized anxiety disorder (GAD), escitalopram reduces symptoms of anxiety, according to a study published online Aug. 25 in The Journal of Clinical Psychiatry.

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Vitamin D Supplement No Benefit in Pediatric Persistent Asthma

TUESDAY, Aug. 25, 2020 (HealthDay News) — Vitamin D3 supplementation does not prolong the time to severe asthma exacerbation among children with persistent asthma and low vitamin D levels, according to a study published in the Aug. 25 issue of the Journal of the American Medical Association.

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Clinical Impact of Remdesivir in Moderate COVID-19 Unclear

MONDAY, Aug. 24, 2020 (HealthDay News) — Patients with moderate COVID-19 receiving a five-day course of remdesivir have a statistically significant difference in clinical status compared with usual care, according to a study published online Aug. 21 in the Journal of the American Medical Association.

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Editorial

School-Located Influenza Vaccine Intervention Beneficial

MONDAY, Aug. 24, 2020 (HealthDay News) — A school-located influenza vaccination (SLIV) intervention is associated with a reduction in the incidence of influenza hospitalization, according to a study published online Aug. 18 in PLOS Medicine.

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Antihypertensive Agents Not Tied to Higher Risk for Depression

MONDAY, Aug. 24, 2020 (HealthDay News) — Nine individual antihypertensive agents from the classes of angiotensin agents, calcium antagonists, and β-blockers are associated with reduced rates of depression, according to a study published online Aug. 24 in Hypertension.

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RAAS Inhibitors May Benefit HTN Patients With COVID-19

MONDAY, Aug. 24, 2020 (HealthDay News) — Renin-angiotensin-aldosterone system (RAAS) inhibitors are beneficial for hypertensive patients with COVID-19, according to a study published online Aug. 24 in Current Atherosclerosis Reports.

Abstract/Full Text

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 17 to 21, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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White House Blocks FDA’s Power to Regulate Lab Tests

FRIDAY, Aug. 21, 2020 (HealthDay News) — The Trump administration has blocked the U.S. Food and Drug Administration from regulating a wide swath of laboratory tests, including ones for COVID-19.

Washington Post Article

Extract From Deadly Plant Touted as COVID-19 Cure

FRIDAY, Aug. 21, 2020 (HealthDay News) — Experts have slammed claims by a major Trump donor that an extract from a deadly plant is a cure for COVID-19.

The New York Times Article

ACIP Issues Recommendations for 2020 to 2021 Flu Vaccination

FRIDAY, Aug. 21, 2020 (HealthDay News) — Advisory Committee on Immunization Practices (ACIP) recommendations have been updated to include the influenza vaccination for the 2020 to 2021 season; the recommendations were published in the Aug. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Adolescent Vaccinations Decreased During COVID-19 Pandemic

FRIDAY, Aug. 21, 2020 (HealthDay News) — The decrease in vaccination orders seen during the COVID-19 pandemic could offset increases in vaccinations for adolescents from 2018 to 2019, according to research published in the Aug. 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Nonopioid Pain Protocol Feasible After Sports Orthopedic Surgery

FRIDAY, Aug. 21, 2020 (HealthDay News) — For patients undergoing common orthopedic sports procedures, a multimodal, nonopioid pain protocol featuring little or no use of opioids is feasible for managing postoperative pain, according to a study published in the August issue of Arthroscopy.

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Short-Term PrEP Feasible for Men at Risk for HIV on Vacation

THURSDAY, Aug. 20, 2020 (HealthDay News) — Preexposure prophylaxis (PrEP) is well tolerated by men who have sex with men (MSM) at episodic risk for HIV while on vacation, according to a study published online Aug. 15 in the Journal of Acquired Immune Deficiency Syndrome.

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Longer Bisphosphonate Use May Up Atypical Femur Fracture Risk

THURSDAY, Aug. 20, 2020 (HealthDay News) — Longer duration of bisphosphonate use is associated with an increased risk for atypical femur fracture, according to a study published in the Aug. 20 issue of the New England Journal of Medicine.

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Evinacumab Cuts LDL-C Level in Familial Hypercholesterolemia

THURSDAY, Aug. 20, 2020 (HealthDay News) — For patients with homozygous familial hypercholesterolemia, evinacumab lowers low-density lipoprotein (LDL) cholesterol levels, according to a study published in the Aug. 20 issue of the New England Journal of Medicine.

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Editorial (subscription or payment may be required)

Antibiotic Exposure Linked to Risk for Inflammatory Bowel Disease

THURSDAY, Aug. 20, 2020 (HealthDay News) — Higher cumulative exposure to antibiotics is associated with an increased risk for new-onset inflammatory bowel disease (IBD), according to a study published online Aug. 17 in The Lancet Gastroenterology & Hepatology.

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HHS: Pharmacists in All States Can Give Childhood Vaccinations

WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Children can now be vaccinated by pharmacists in all 50 states as the U.S. government seeks to prevent a decline in routine vaccinations during the COVID-19 pandemic.

AP News Article

Honey Beats Usual Care for Upper Respiratory Tract Infections

WEDNESDAY, Aug. 19, 2020 (HealthDay News) — For upper respiratory tract infections (URTIs), honey seems superior to usual care, according to a review and meta-analysis published online Aug. 18 in BMJ Evidence-Based Medicine.

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CNS-Active Meds Often Prescribed for Older Adults With Dementia

WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Patients with dementia are frequently prescribed central nervous system (CNS)-active medications, according to a research letter published online Aug. 18 in the Journal of the American Medical Association.

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Antibiotics May Reduce Efficacy of Hormonal Contraceptives

WEDNESDAY, Aug. 19, 2020 (HealthDay News) — The efficacy of hormonal contraceptives may be reduced with use of antibiotics, according to a study published online Aug. 18 in BMJ Evidence-Based Medicine.

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Combination Therapy May Benefit Some With Kawasaki Disease

WEDNESDAY, Aug. 19, 2020 (HealthDay News) — Adding corticosteroids to initial intravenous immunoglobulin seems beneficial for preventing coronary artery abnormalities in high-risk patients with Kawasaki disease (KD), according to a study published online Aug. 19 in the Journal of the American Heart Association.

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Editorial

Bariatric Surgery Linked to Reduction in Mortality Rate

TUESDAY, Aug. 18, 2020 (HealthDay News) — Bariatric surgery is associated with a reduction in mortality, and Roux-en-Y gastric bypass (RYGB) is effective for blood pressure (BP) control in patients with hypertension and obesity, according to two studies published online Aug. 18 in the Annals of Internal Medicine.

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Rates of Prescription Opioid Use Higher in Cancer Survivors

TUESDAY, Aug. 18, 2020 (HealthDay News) — Cancer survivors have higher rates of prescription opioid use but do not have increased rates of prescription opioid misuse compared with those without a history of cancer, according to a study published online Aug. 17 in JAMA Network Open.

Abstract/Full Text

ACP, AAFP Issue Guidelines for Acute Musculoskeletal Injuries

TUESDAY, Aug. 18, 2020 (HealthDay News) — Topical nonsteroidal anti-inflammatory drugs (NSAIDs) are recommended for the treatment of acute pain from non-low back, musculoskeletal injuries, according to a clinical guideline developed by the American College of Physicians (ACP) and the American Academy of Family Physicians (AAFP) and published online Aug. 18 in the Annals of Internal Medicine.

Clinical Guideline
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Pitavastatin Effective for Lowering Lipids

MONDAY, Aug. 17, 2020 (HealthDay News) — Pitavastatin lowers blood total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides in a dose-dependent manner, according to a review recently published in the Cochrane Database of Systematic Reviews.

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Factors Tied to Hormone Therapy Use After Oophorectomy ID’d

MONDAY, Aug. 17, 2020 (HealthDay News) — Age at surgery, education level, and preventive mastectomy are associated with hormone therapy (HT) use after preventive oophorectomy in BRCA mutation carriers, according to a study published online Aug. 10 in Menopause.

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Shift Occurring in Deadly Overdoses

FRIDAY, Aug. 14, 2020 (HealthDay News) — There has been a dramatic increase in overdose fatalities involving illicit opioids, stimulants, heroin, and cocaine but a simultaneous dramatic drop in the use of prescription opioids, according to the Opioid Task Force 2020 Progress Report released by the American Medical Association (AMA).

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 10 to 14, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Racial, Ethnic Disparities in Flu Shot Seen at Dialysis Facilities

FRIDAY, Aug. 14, 2020 (HealthDay News) — For U.S. patients undergoing dialysis, the proportion receiving influenza vaccination is lower at facilities with higher proportions of Black and Hispanic patients, according to a study published online Aug. 13 in the Journal of the American Society of Nephrology.

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Bisphosphonates Safe but May Not Improve Bone Marrow Lesion Volume

FRIDAY, Aug. 14, 2020 (HealthDay News) — There is no clear benefit of bisphosphonates on bone marrow lesions (BMLs), according to a study published online Aug. 4 in Osteoarthritis and Cartilage.

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U.S. COVID-19 Death Tally Hits New High for Summer

THURSDAY, Aug. 13, 2020 (HealthDay News) — America logged its highest single-day COVID-19 death total of the summer on Wednesday, as the toll from an earlier surge in cases in Sun Belt states continued to mount.

The New York Times Article

FDA Warns of Hand Sanitizers Tainted With 1-Propanol

THURSDAY, Aug. 13, 2020 (HealthDay News) — The U.S. Food and Drug Administration is warning people not to use hand sanitizers made by Harmonic Nature S de RL de MI in Mexico.

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Physicians Do Not See They Are Part of Antibiotic Rx Problem

THURSDAY, Aug. 13, 2020 (HealthDay News) — Primary care physicians generally do not recognize antibiotic resistance and inappropriate prescribing as issues in their practice, according to a study published in the July issue of Open Forum Infectious Diseases.

Abstract/Full Text

GI Surgical Outcomes Worse With Preop Use of Opioids, Sedatives

THURSDAY, Aug. 13, 2020 (HealthDay News) — Preoperative opioid and sedative use are risk factors for morbidity and mortality following colorectal resections, according to a study published in the July issue of Diseases of the Colon & Rectum.

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U.S. Government to Buy 100 Million Doses of COVID-19 Vaccine From Moderna

WEDNESDAY, Aug. 12, 2020 (HealthDay News) — The Trump administration has agreed to pay $1.5 billion for 100 million doses of a COVID-19 vaccine from Moderna once it is approved, CNN reported Wednesday.

CNN Article

ASH Issues Guidelines on Newly Diagnosed AML in Older Adults

WEDNESDAY, Aug. 12, 2020 (HealthDay News) — In evidence-based guidelines issued by the American Society of Hematology and published in the Aug. 11 issue of Blood Advances, recommendations are presented for the management of newly diagnosed acute myeloid leukemia (AML) in older adults.

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Self-Reported Biotin Use Increased From 1999 to 2016

WEDNESDAY, Aug. 12, 2020 (HealthDay News) — From 1999 to 2016, the prevalence of self-reported biotin supplement use increased, especially among women and older adults, according to a research letter published in the Aug. 11 issue of the Journal of the American Medical Association.

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Preventable Hospitalizations Up Among Those With Dementia

WEDNESDAY, Aug. 12, 2020 (HealthDay News) — The number of potentially preventable hospitalizations among older adults with dementia is increasing, according to a study published online July 23 in the Journal of the American Geriatrics Society.

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Bacterial Infections Increase Coronary Heart Disease Risk in T1DM

WEDNESDAY, Aug. 12, 2020 (HealthDay News) — Bacterial infections are associated with an increased risk for incident coronary heart disease (CHD) in individuals with type 1 diabetes, according to a study published online Aug. 4 in the Journal of Internal Medicine.

Abstract/Full Text

FDA Head Says Any Approved COVID-19 Vaccine Will Be Safe

TUESDAY, Aug. 11, 2020 (HealthDay News) — Stephen Hahn, M.D., the head of the U.S. Food and Drug Administration, said Monday that the agency will not compromise safety when approving a COVID-19 vaccine, CNN reported.

CNN Article

Gilead Seeks FDA Approval for Remdesivir

TUESDAY, Aug. 11, 2020 (HealthDay News) — Gilead Sciences has applied to the U.S. Food and Drug Administration for approval for its COVID-19 treatment, remdesivir. The antiviral drug will take the brand name Veklury, the company said.

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Russia Approves COVID-19 Vaccine Before Trials Completed

TUESDAY, Aug. 11, 2020 (HealthDay News) — Before completing clinical trials to ensure the vaccine is safe and effective, the Russian government has gone ahead and approved a vaccine against the new coronavirus, The New York Times reported Tuesday.

The New York Times Article

Prenatal Cannabis Exposure May Harm Child Neurodevelopment

TUESDAY, Aug. 11, 2020 (HealthDay News) — Cannabis use during pregnancy is associated with an increased risk of neurodevelopmental disorders in offspring by age 10 years, according to a study published Aug. 10 in Nature Medicine.

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Some Occult Overdose Deaths Misclassified as Cardiac Arrests

TUESDAY, Aug. 11, 2020 (HealthDay News) — A considerable proportion of deaths attributed to out-of-hospital cardiac arrest (OHCA) are actually caused by occult overdose, according to a research letter published online Aug. 11 in the Annals of Internal Medicine.

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Persistent Opioid Use Seen in ~10 Percent of Patients After Cardiac Surgery

TUESDAY, Aug. 11, 2020 (HealthDay News) — Persistent opioid use is a common concern after cardiac surgery, according to a study published online June 17 in JAMA Cardiology.

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Expanding Medicaid in Holdout States Could Insure 3.9 Million

MONDAY, Aug. 10, 2020 (HealthDay News) — Expanding Medicaid to all states could reduce the number of uninsured by 28 percent based on pre-COVID-19 data, according to a report released by the Urban Institute and the Robert Wood Johnson Foundation.

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Serine 91 Genotype of gyrA Gonorrhea Successfully Treated With Ciprofloxacin

MONDAY, Aug. 10, 2020 (HealthDay News) — For patients with gonorrhea, detection of the wild-type serine 91 genotype of the gyrA gene of Neisseria gonorrhoeae is predictive of a successful treatment outcome with ciprofloxacin, according to a study published online Aug. 7 in Clinical Infectious Diseases.

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Two-Thirds of U.S. Adults Likely to Get COVID-19 Vaccine

MONDAY, Aug. 10, 2020 (HealthDay News) — Two-thirds of U.S. adults say they would get a COVID-19 vaccine, according to the results of a survey released Aug. 6 by the COVID-19 Consortium for Understanding the Public’s Policy Preferences Across States.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Aug. 3 to 7, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Life Expectancy 78.60 Years for U.S. Population for 2009-2011

FRIDAY, Aug. 7, 2020 (HealthDay News) — Life expectancy for 2009 to 2011 was 78.60 years for the total U.S. population, with the highest life expectancy for Hispanic women, according to the Aug. 7 National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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Moderna Charging Much More for COVID-19 Vaccine Than Others

FRIDAY, Aug. 7, 2020 (HealthDay News) — Moderna is charging $37 a dose for its experimental vaccine, which is far more than what other companies say they plan to charge for their vaccines, CBS News reported Wednesday. Because two doses of the vaccine are needed to immunize people from COVID-19, total costs could be $74 per person.

CBS News Article

Short-Term Risk for Below-Knee Amputation Not Increased With SGLT2i

FRIDAY, Aug. 7, 2020 (HealthDay News) — For patients with type 2 diabetes, sodium glucose cotransporter 2 (SGLT2) inhibitors do not increase the risk for below-knee amputation compared with dipeptidyl peptidase 4 (DPP-4) inhibitors, according to a study published online Aug. 5 in Diabetes Care.

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Longer Bisphosphonate Drug Holiday May Up Fracture Risk

FRIDAY, Aug. 7, 2020 (HealthDay News) — In patients who have previously suffered a vertebral fracture, a longer bisphosphonate (BP) drug holiday is associated with an increased risk for major osteoporotic fractures (MOFs), according to a study published online in the September issue of Bone.

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Scientists Call for Broader Use of Faster COVID-19 Tests

THURSDAY, Aug. 6, 2020 (HealthDay News) — As COVID-19 cases continue to surge across America, scientists on Wednesday called for widespread adoption of simpler, less accurate tests, as long as they are given often and quickly.

The New York Times Article

Johnson & Johnson Makes $1 Billion Vaccine Deal

THURSDAY, Aug. 6, 2020 (HealthDay News) — The U.S. government will pay Johnson & Johnson $1 billion for 100 million doses of its vaccine if it is approved by the U.S. Food and Drug Administration, the Washington Post reported Wednesday.

Washington Post Article

Early Use of IL-6 Inhibitors May Improve COVID-19 Outcomes

THURSDAY, Aug. 6, 2020 (HealthDay News) — For patients with severe COVID-19, administration of an interleukin-6 receptor inhibitor (IL6ri) earlier in the disease course is associated with improved outcomes, according to a study published online July 25 in the International Journal of Infectious Diseases.

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ASCRS Updates Guidelines on Surgery for Crohn Disease

THURSDAY, Aug. 6, 2020 (HealthDay News) — In clinical practice guidelines from the American Society of Colon and Rectal Surgeons, published in the August issue of Diseases of the Colon & Rectum, recommendations are presented for indications and considerations before, during, and after surgery for Crohn disease (CD).

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Vitamin D/Calcium Reduces Benign Paroxysmal Positional Vertigo

THURSDAY, Aug. 6, 2020 (HealthDay News) — For patients with benign paroxysmal positional vertigo (BPPV), a vitamin D and calcium supplementation intervention is beneficial for preventing recurrences, according to a study published online Aug. 5 in Neurology.

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Relapse Rates Lower With Ofatumumab in Multiple Sclerosis

THURSDAY, Aug. 6, 2020 (HealthDay News) — Among patients with relapsing multiple sclerosis, annualized relapse rates are lower for those receiving anti-CD20 monoclonal antibody ofatumumab compared with teriflunomide, according to a study published in the Aug. 6 issue of the New England Journal of Medicine.

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AHA: Cannabis May Have Adverse Cardiovascular Effects

THURSDAY, Aug. 6, 2020 (HealthDay News) — Cannabis seems not to be associated with cardiovascular benefits but has adverse cardiovascular effects, according to a scientific statement from the American Heart Association published online Aug. 5 in Circulation.

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Experimental COVID-19 Vaccine Shows Encouraging Results

WEDNESDAY, Aug. 5, 2020 (HealthDay News) — Maryland-based Novavax said Tuesday that preliminary trials of an experimental COVID-19 vaccine were promising.

The New York Times Article

Seven States Join Pact to Speed COVID-19 Testing

WEDNESDAY, Aug. 5, 2020 (HealthDay News) — As the daily U.S. COVID-19 death toll averaged more than 1,000 for the ninth straight day on Tuesday, governors from seven states banded together to shorten turnaround time for COVID-19 test results.

The New York Times Article
CNN Article

CV Meds Underused in Hispanics With Peripheral Artery Disease

WEDNESDAY, Aug. 5, 2020 (HealthDay News) — Individuals of Hispanic/Latino background with known peripheral artery disease (PAD) have the lowest use of all classes of cardiovascular medications, according to a study published online Aug. 5 in the Journal of the American Heart Association.

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Health Plans Not Implementing Prior Authorization Reforms

WEDNESDAY, Aug. 5, 2020 (HealthDay News) — Physicians say prior authorization (PA) continues to interfere with patient care and can lead to adverse clinical consequences, according to the results of a survey released by the American Medical Association.

Press Release
Physician Survey

Most Studies Still Fail to Analyze Data by Sex

TUESDAY, Aug. 4, 2020 (HealthDay News) — The effect of gender is still largely ignored in scientific studies, according to a study published online June 9 in eLife.

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Burnout High Among Nonphysician Frontline Health Care Workers

TUESDAY, Aug. 4, 2020 (HealthDay News) — More than 40 percent of nurses on the front lines during the pandemic may be experiencing burnout, according to a research letter published online Aug. 4 in JAMA Network Open.

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β2-Agonists Improve Nonaerobic Athletic Performance

TUESDAY, Aug. 4, 2020 (HealthDay News) — Sprint and strength performance are improved in nonasthmatic athletes by using β2-agonists, according to a review published online Aug. 3 in the British Journal of Sports Medicine.

Abstract/Full Text

Vitamin D3 Does Not Reduce Depression Incidence, Recurrence

TUESDAY, Aug. 4, 2020 (HealthDay News) — Treatment with vitamin D3 versus placebo does not result in a significant difference in the incidence and recurrence of depression or clinically relevant depressive symptoms or in a change in mood scores among adults aged 50 years or older without clinically relevant depressive symptoms, according to a study published in the Aug. 4 issue of the Journal of the American Medical Association.

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Program Cuts Outpatient Antibiotic Rx for Peds Respiratory Infections

TUESDAY, Aug. 4, 2020 (HealthDay News) — A distance learning program is effective for reducing outpatient prescribing for pediatric acute respiratory tract infection (ARTI) visits, according to a study published online Aug. 3 in Pediatrics.

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Editorial (subscription or payment may be required)

Probiotics Not Recommended for Most Digestive Conditions

TUESDAY, Aug. 4, 2020 (HealthDay News) — Probiotics are not recommended for most digestive conditions, according to a clinical practice guideline issued by the American Gastroenterological Association and published online June 9 in Gastroenterology.

AGA Clinical Practice Guidelines
Technical Review

Canakinumab Explored as Therapy for Large-Joint Osteoarthritis

MONDAY, Aug. 3, 2020 (HealthDay News) — Inhibition of interleukin-1β (IL-1β) with canakinumab seems to reduce the incidence of total hip replacement/total knee replacement (THR/TKR) compared with placebo, according to an exploratory analysis published online Aug. 4 in the Annals of Internal Medicine.

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Cost-Related Rx Nonadherence Highest in Young U.S. Women

MONDAY, Aug. 3, 2020 (HealthDay News) — Cost-related prescription nonadherence is highest among younger U.S. women compared with individuals living in 10 other high-income countries, according to a report published in the August issue of Health Affairs.

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Cannabidiol Studied as Potential Treatment for Cannabis Use Disorder

MONDAY, Aug. 3, 2020 (HealthDay News) — Abstinence from cannabis is increased with daily oral doses of cannabidiol 400 mg and 800 mg versus placebo, according to a dose-finding study published online July 28 in The Lancet Psychiatry.

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Botox Injections May Ease Depression

MONDAY, Aug. 3, 2020 (HealthDay News) — Botox injections, which are commonly used to lessen wrinkles, migraines, muscle spasms, excessive sweating, and incontinence, may also help treat depression, according to a study published online July 30 in Scientific Reports.

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More Than One in Three Stroke Survivors Have Uncontrolled HTN

MONDAY, Aug. 3, 2020 (HealthDay News) — More than one-third of stroke survivors have uncontrolled hypertension, and about one in five are not taking antihypertensive medications, according to a study published online July 27 in JAMA Neurology.

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Short Video May Lower Parent Interest in Antibiotics for Child

MONDAY, Aug. 3, 2020 (HealthDay News) — A 90-second animated video can reduce parents’ interest in receiving antibiotics for their child’s respiratory infection, according to a study published online June 15 in The Journal of Pediatrics.

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