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April 2018 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for April 2018. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Review: Need to Strengthen Natural Experiments in Obesity

MONDAY, April 30, 2018 (HealthDay News) — Based on findings from a systematic review of the literature, recommendations have been developed for improving the evidence for natural experiments in obesity; the review and position paper were published online May 1 in the Annals of Internal Medicine.

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Irregular Menstruation Common in Girls With Type 2 Diabetes

MONDAY, April 30, 2018 (HealthDay News) — Menstrual dysfunction is common in girls with recently diagnosed type 2 diabetes, and does not improve with two years of anti-hyperglycemic treatment, according to a study published online April 24 in the Journal of Clinical Endocrinology & Metabolism.

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New Clinic Satisfaction Tool Provides Real-Time Feedback

THURSDAY, April 26, 2018 (HealthDay News) — A new clinic satisfaction tool improves communication and provides real-time feedback, according to a study published online April 14 in Neurosurgery.

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High Risk of Death After Major Diabetes-Related Amputations

FRIDAY, April 27, 2018 (HealthDay News) — There is a high risk of postoperative mortality among patients undergoing lower-limb amputation, according to a study published online April 5 in Diabetes Care.

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Hemoglobin A1c Levels Not Tied to Wound Outcomes

THURSDAY, April 26, 2018 (HealthDay News) — There does not appear to be a clinically meaningful association between baseline or prospective hemoglobin A1c (A1C) and wound healing in patients with diabetic foot ulcers (DFUs), according to a study published online April 16 in Diabetes Care.

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Improvement in Race-Based Disparities in Years of Life Lost

THURSDAY, April 26, 2018 (HealthDay News) — From 1990 to 2014 there was a decrease in race-based disparities in years of life lost (YLL) in the United States, according to a study published online April 25 in PLOS ONE.

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Pros and Cons for E-Cigarettes As Aid to Smoking Cessation

THURSDAY, April 26, 2018 (HealthDay News) — Evidence relating to the pros and cons of electronic cigarettes (e-cigarettes) as helpful smoking cessation tools is presented and discussed in a head to head article published online April 25 in The BMJ.

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Saturday Is National Prescription Drug Take Back Day

THURSDAY, April 26, 2017 (HealthDay News) — The U.S. Drug Enforcement Administration and local agencies are holding the 15th National Prescription Drug Take Back Day across the country this Saturday, April 28.

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Medicare Requiring Hospitals to Post Prices Online

WEDNESDAY, April 25, 2018 (HealthDay News) — U.S. hospitals will have to post their standard prices online and make it easier for patients to access their electronic medical records, Medicare officials said Tuesday.

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About 40 Percent of Men Report Experiencing Weight Stigma

WEDNESDAY, April 25, 2018 (HealthDay News) — A substantial proportion of men report experiencing weight stigma, according to a study published online April 23 in Obesity.

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Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

WEDNESDAY, April 25, 2018 (HealthDay News) — For patients with type 2 diabetes, aortic stiffness is associated with concentric left ventricular (LV) remodeling, according to a study published online April 16 in Diabetes.

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Exercise Intervention Doesn’t Improve Walking Ability in PAD

TUESDAY, April 24, 2018 (HealthDay News) — For patients with peripheral artery disease (PAD), a home-based exercise intervention does not improve walking ability over nine months compared with usual care, according to a study published in the April 24 issue of the Journal of the American Medical Association.

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Evening Preference Linked to Higher BMI in Type 2 Diabetes

TUESDAY, April 24, 2018 (HealthDay News) — Evening preference and a later breakfast are associated with elevated body mass index (BMI) in adults with type 2 diabetes, according to a study published online April 13 in Diabetic Medicine.

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Factors ID’d to Predict Fatty Liver in Obese Teens

MONDAY, April 23, 2018 (HealthDay News) — Ethnicity/race, markers of insulin resistance, and genetic factors might help identify obese youth at risk for developing fatty liver, according to a study published online April 17 in Hepatology.

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Patients Prefer Doctors Who Engage in Face-to-Face Visits

MONDAY, April 23, 2018 (HealthDay News) — Patients prefer physicians who engage in face-to-face (F2F) clinic visits, rather than those using an examination room computer (ERC), according to a research letter published online April 19 in JAMA Oncology.

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Age- and Weight-Based Screening Identifies Half With Prediabetes

MONDAY, April 23, 2018 (HealthDay News) — Targeted diabetes screening based only on age and weight criteria will identify approximately half of U.S. adults with dysglycemia, according to a study published online April 12 in the Journal of General Internal Medicine.

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Choroidal Thickness Changes in Patients With Untreated DM

MONDAY, April 23, 2018 (HealthDay News) — The choroidal thickness changes in patients with untreated diabetes mellitus over time, according to a study published online April 14 in Clinical & Experimental Ophthalmology.

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In LVSD, Diabetes Tied to Higher Risk of Heart Failure

FRIDAY, April 20, 2018 (HealthDay News) — In patients with asymptomatic left ventricular systolic dysfunction, diabetes is associated with an increased risk of developing heart failure, according to a study published online April 6 in Diabetes Care.

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Artificial Pancreas Treatment Efficacious for Type 1 Diabetes

THURSDAY, April 19, 2018 (HealthDay News) — For patients with type 1 diabetes, artificial pancreas treatment is efficacious, increasing the proportion of time spent in the near normoglycemic range, according to a study published online April 18 in The BMJ.

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Social Support of Autonomy Tied to Better Glycemic Control in DM

WEDNESDAY, April 18, 2018 (HealthDay News) — Family and friends’ autonomy support may lead to better glycemic control by reducing distress among patients with diabetes, according to a study published online March 29 in Diabetes Care.

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Young Adults With T1DM Show Muscle Metabolic Deficiencies

WEDNESDAY, April 18, 2018 (HealthDay News) — Physically active young adults with type 1 diabetes have alterations in mitochondrial ultrastructure and bioenergetics within skeletal muscle, according to a study published online April 18 in Diabetologia.

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Metabolic Syndrome Common With Chronic Hep B Infection

TUESDAY, April 17, 2018 (HealthDay News) — Metabolic syndrome (MetS) is prevalent among patients with chronic hepatitis B (HBV) infection, according to a study published online March 29 in Diabetes Care.

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Recommendations Developed on Gender Equity in Medicine

MONDAY, April 16, 2018 (HealthDay News) — In a position paper published online April 17 in the Annals of Internal Medicine, recommendations are provided aimed at addressing gender equity in physician compensation and career advancement opportunities.

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TFs Operate Across Gene Loci Within Disease Phenotypes

MONDAY, April 16, 2018 (HealthDay News) — Transcription factors (TFs) seem to operate across gene loci, according to a study published online April 16 in Nature Genetics.

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Nonoptimized Drug Therapy Costs More Than $500 Billion Annually

MONDAY, April 16, 2018 (HealthDay News) — The estimated annual cost of drug-related morbidity and mortality resulting from nonoptimized medication therapy is more than half a trillion dollars in the United States, according to a study published online March 26 in the Annals of Pharmacotherapy.

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One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

MONDAY, April 16, 2018 (HealthDay News) — One- and two-hour plasma glucose concentrations (1h-PG and 2h-PG, respectively) are similarly effective at predicting diabetic retinopathy (DR), according to a study published online April 5 in Diabetes Care.

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FDA Approves AI Device to Detect Diabetic Retinopathy

FRIDAY, April 13, 2018 (HealthDay News) — Artificial intelligence software that can detect diabetic retinopathy has been approved by the U.S. Food and Drug Administration.

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Negative Affect That Lingers Tied to Health 10 Years Later

FRIDAY, April 13, 2018 (HealthDay News) — Negative affect that lingers is associated with worse physical health outcomes almost 10 years later, according to a study published online March 19 in Psychological Science.

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Continuous Glucose Monitoring Cost-Effective in T1DM

FRIDAY, April 13, 2018 (HealthDay News) — For adults with type 1 diabetes (T1D) with suboptimal control despite using multiple insulin injections, continuous glucose monitoring (CGM) seems cost-effective, with improved glucose control, according to a study published online April 12 in Diabetes Care.

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Soda Tax Cuts Daily Soda, Energy Drink Consumption

FRIDAY, April 13, 2018 (HealthDay News) — A soda tax does influence daily consumption of regular soda, energy drinks, and bottled water, according to a study published online April 12 in the American Journal of Preventive Medicine.

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Recent Years Saw Increase in Burden of Prior Authorization

THURSDAY, April 12, 2018 (HealthDay News) — The burden of prior authorization (PA) has increased over the past five years, and 92 percent of physicians report associated delays in access to care, according to the results of a survey published by the American Medical Association (AMA).

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Pharmacists Can Help With DM Management Via Telemedicine

THURSDAY, April 12, 2018 (HealthDay News) — Pharmacist use of telemedicine is a promising vehicle for improving patient management of diabetes, according to an article published in Drug Topics.

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Higher Mortality Risk Seen for ‘Night Owls’

THURSDAY, April 12, 2018 (HealthDay News) — Individuals with a later chronotype have increased mortality risk, according to a study published online April 12 in Chronobiology International.

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Cigarette Price Hike Would Provide More Gains for the Poor

THURSDAY, April 12, 2018 (HealthDay News) — An increase in the market prices of cigarettes would provide more health and financial gains to the poorest 20 percent of the population, according to a study published online April 11 in The BMJ.

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Pre-Pregnancy Fitness Lowers Gestational Diabetes Risk

THURSDAY, April 12, 2018 (HealthDay News) — Higher pre-pregnancy fitness lowers the risk of gestational diabetes mellitus (GDM), according to a study published online March 8 in Medicine & Science in Sports & Exercise.

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Declines Seen in Cardiovascular Risk Factors From 1990 to 2010

WEDNESDAY, April 11, 2018 (HealthDay News) — Among adults aged 40 years and older, cardiovascular risk decreased in men from 1990 to 2010 and increased followed by a decrease in women over the same time period, according to a study published online March 22 in Aging Clinical and Experimental Research.

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No Reduced CVD Risk for SBP <120 mm Hg in Type 2 Diabetes

WEDNESDAY, April 11, 2018 (HealthDay News) — For patients with type 2 diabetes mellitus (T2DM), there is no reduction in cardiovascular disease (CVD) risk with achieved systolic blood pressure (SBP) of <120 mm Hg versus <130 or <140 mm Hg, according to a study published online March 28 in Diabetes Care.

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Metabolic Syndrome Common in Patients With Lupus

TUESDAY, April 10, 2018 (HealthDay News) — As with the general population, metabolic syndrome (MetS) is common among patients with systemic lupus erythematosus (SLE), according to a study published online April 3 in the International Journal of Rheumatic Diseases.

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Polycystic Ovary Syndrome Tied to Risk of Mental Health Issues

TUESDAY, April 10, 2018 (HealthDay News) — Polycystic ovary syndrome (PCOS) is associated with higher risk of psychiatric conditions, according to a study published online April 10 in the Journal of Clinical Endocrinology & Metabolism.

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Suggestions Offered to Reduce Physician Frustration With EHRs

TUESDAY, April 10, 2018 (HealthDay News) — Changes can be implemented to help reduce physician frustration with electronic health records (EHRs), according to an article published in Medical Economics.

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Considerable Differences in Burden of Disease at State Level

TUESDAY, April 10, 2018 (HealthDay News) — There are considerable differences in the burden of disease at the state level, according to a study published in the April 10 issue of the Journal of the American Medical Association.

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DPP-4I Not Tied to Increased Risk of Acute Pancreatitis in Seniors

TUESDAY, April 10, 2018 (HealthDay News) — For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care.

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Adult Patients With Diabetes Go to Dentist Less Often

MONDAY, April 9, 2018 (HealthDay News) — People with diabetes and prediabetes visit the dentist less often than people without diabetes, according to a study published online March 31 in the Journal of the American Dental Association.

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Eating Pecans May Cut Risk of Cardiovascular Disease, Diabetes

FRIDAY, April 6, 2018 (HealthDay News) — Eating pecans every day for four weeks improves certain markers of cardiometabolic disease risk, according to a study published online March 11 in Nutrients.

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Interns’ Schedule Takes Toll on Sleep, Physical Activity, Mood

FRIDAY, April 6, 2018 (HealthDay News) — New interns’ intense and changing schedules take a toll on sleep, activity, and mood, according to a study published online March 14 in the Journal of General Internal Medicine.

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Glycemic Extremes in T1DM Impact Cognitive Skills in Kids

FRIDAY, April 6, 2018 (HealthDay News) — Type 1 diabetes is associated with cognitive dysfunction in children, according to a review published online March 23 in the Journal of Diabetes Investigation.

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ACA Marketplaces Expand Coverage for Chronically Ill

THURSDAY, April 5, 2018 (HealthDay News) — The Affordable Care Act’s Marketplaces covered a disproportionate share of non-elderly adults with high health care risks in the 2014 to 2015 time period, according to a study published in the April issue of Health Affairs.

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Online Doc Reviews Don’t Reflect Patient Satisfaction Surveys

THURSDAY, April 5, 2018 (HealthDay News) — Online physician reviews do not reflect patient satisfaction surveys (PSSs), according to a study published in the April issue of the Mayo Clinic Proceedings.

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Lactation Lowers Risk of T2DM After Gestational Diabetes

THURSDAY, April 5, 2018 (HealthDay News) — For women with previous gestational diabetes mellitus (GDM), lactation is associated with reduced risk of type 2 diabetes mellitus (T2DM), although there is no benefit for long-term lactation, according to a review and meta-analysis published online March 25 in the Journal of Diabetes Investigation.

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Smoking Status Associated With Poor Diet Quality

THURSDAY, April 5, 2018 (HealthDay News) — Smokers have lower quality diets than former smokers and nonsmokers, according to a study published online April 4 in BMC Public Health.

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Variations Identified in Free-Text Directions in E-Prescriptions

WEDNESDAY, April 4, 2018 (HealthDay News) — There is considerable variation in the quality of free-text patient directions (Sig) in electronic prescriptions (e-prescriptions), according to a study published online April 2 in the Journal of Managed Care & Specialty Pharmacy.

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Depressive Symptoms Tied to Diabetes Self-Management

WEDNESDAY, April 4, 2018 (HealthDay News) — Changes in depressive symptoms can predict improvement in self-efficacy and adherence to diabetes management, according to a study published online March 27 in Diabetes Care.

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Diabetes, HbA1c Linked to Adverse Outcomes After Surgery

TUESDAY, April 3, 2018 (HealthDay News) — For surgical inpatients aged ≥54 years, diabetes and increased hemoglobin A1c (HbA1c) are associated with increased risk of adverse outcomes, according to a study published online March 26 in Diabetes Care.

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