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Monthly Archives: November 2019

Most estimates show no differences in effectiveness between classes of antihypertensive agents

Equivalence Seen Between Drug Classes for HTN Monotherapy

Thiazide, thiazide-like diuretics superior to ACEi; nondihydropyridine calcium channel blockers inferior
Adalimumab exposure in pregnancy does not increase the risk for birth defects

Risk for Birth Defects Not Increased With Adalimumab

Risk for preterm delivery higher in women with RA, Crohn disease regardless of adalimumab exposure
Survivors of chronic lymphocytic leukemia have an increased risk for second primary malignancy

Risk for Second Primary Malignancy Up in CLL Survivors

SPM risk higher for men and nonwhites, after chemotherapy, for recent years of diagnosis, for advanced age
For patients with cystic fibrosis with Phe508del-minimal function genotypes

Elexacaftor-Tezacaftor-Ivacaftor Efficacious for Cystic Fibrosis

Percentage of FEV1 higher at four weeks and through 24 weeks with treatment versus placebo