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Monthly Archives: November 2018

Cardiovascular risk should be carefully evaluated in patients with psoriatic arthritis

Higher Cardiovascular Risk Seen With Psoriatic Arthritis

Risk seems to be increased especially in patients with a high inflammatory burden, late-onset psoriasis
Both rotating night shift work and unhealthy lifestyle are associated with an increased risk for type 2 diabetes among female nurses

Rotating Night Shift Work, Lifestyle Factors Linked to T2DM

Significant additive interaction identified for night shift work, unhealthy lifestyle for female nurses
Burnout

Burnout, Satisfaction Vary With Age, Sex Among Neurologists

Sex does not independently predict burnout, fatigue, overall quality of life after controlling for age
The incidence of myocardial infarction is higher in men than women

Several Risk Factors More Strongly Linked to MI in Women

Blood pressure, smoking, type 1 and 2 diabetes linked to higher hazard ratios for women than men
The interpretation of genomic epilepsy tests has evolved rapidly in the last five years

Results of Pediatric Genomic Epilepsy Tests Often Reclassified

Over 30 percent of pediatric patients with genetic dx, undiagnosed conditions had results reclassified
Xospata (gilteritinib) tablets were approved today by the U.S. Food and Drug Administration for treatment of relapsed or refractory acute myeloid leukemia (AML) in adults with an FLT3 mutation

FDA Approves Treatment for AML Patients With Gene Mutation

Expanded approval also granted to mutation assay used to detect FLT3 mutation in AML patients
Firdapse (amifampridine) tablets have been approved by the U.S. Food and Drug Administration for adults with Lambert-Eaton myasthenic syndrome.

FDA Approves Firdapse for Rare Autoimmune Disorder

First agency-sanctioned treatment for adults with Lambert-Eaton myasthenic syndrome
Risk for heat-related disease and death is rising worldwide due to climate change

Climate Change Ups Heat Deaths, Especially Among Elderly

More people vulnerable to heat exposure, potentially causing heat stress, heart and kidney disease
Most proposed bills in state legislatures from 2011 to 2017 sought to expand access to immunization exemptions

Most Bills Enacted Into Law Limit Vaccine Exemptions

However, more than half of proposed bills sought to expand access to immunization exemptions
Being overweight likely plays a causal role in the development of depression

Genetic Analysis Shows Higher BMI May Up Risk for Depression

Findings based on large study assessing genetic causal link, even without metabolic effects